Lipids and Lipid Derivatives
Medchemexpress LLC ACTH (11-24) acetate | 99.88% | 1652.04 | 10 MG
ACTH (11-24) (acetate) is an adrenocorticotropic hormone (ACTH) receptor antagonist. It is a fragment of adrenocorticotropic and induces cortisol release. This compound can be used for research of the central nervous system. In vitro, ACTH (11-24) (acetate) elicits cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells, and in vivo, it has slight influences on circulating plasma corticosterone values and on fighting behavior.
- Adrenocorticotropic hormone (ACTH) receptor antagonist
- Induces cortisol release
- Suitable for research of the central nervous system
- Purity of 99.88%
- Molecular weight of 1652.04 (free base)
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.9% | C32H38N2O5 | 25 MG
Bazedoxifene (acetate)-B is the B-crystal form compound of Bazedoxifene acetate. Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM for ERα and 99 nM for ERβ.
- B-crystal form compound of bazedoxifene acetate
- Orally active nonsteroidal selective estrogen receptor modulator
- IC50s of 23 nM for ERα and 99 nM for ERβ
- Solid appearance
- For research use only
- Stable under recommended storage conditions
Medchemexpress LLC Velmupressin acetate | 1647120-04-4 | 99.5% | 1006.63 | 10 MG
Velmupressin acetate is a potent, selective, and short-acting peptidic V2 receptor (V2R) agonist. It exhibits high affinity for both human (hV2R) and rat (rV2R) V2 receptors, with EC50s of 0.07 nM and 0.02 nM respectively. This product is intended for research purposes only.
- Potent and selective V2 receptor agonist
- Short-acting peptidic compound
- High affinity for human and rat V2 receptors
- For research purposes only
Medchemexpress LLC Velmupressin acetate | 1647120-04-4 | 1006.64 g/mol | 1 MG
Velmupressin acetate is a potent, selective, and short-acting peptidic V2 receptor (V2R) agonist. It exhibits EC50 values of 0.07 nM for human V2R (hV2R) and 0.02 nM for rat V2R (rV2R). This product is stable under recommended storage conditions and is not classified as a hazardous substance or mixture according to safety data.
- Potent, selective, and short-acting peptidic V2 receptor (V2R) agonist
- EC50 values of 0.07 nM for human V2R (hV2R)
- EC50 values of 0.02 nM for rat V2R (rV2R)
- Stable under recommended storage conditions
- Not a hazardous substance or mixture
- For research use only
Apexbio Technology LLC Deoxycorticosterone acetate 56-47-3 50mg
Deoxycorticosterone acetate (56-47-3) is a small-molecule agonist targeting mineralocorticoid receptors (MR) It is designed to activate MR thereby regulating renal sodium reabsorption and potassium excretion Deoxycorticosterone acetate exerts its biological activity primarily through interaction with cytoplasmic mineralocorticoid receptors leading to nuclear translocation and modulation of electrolyte balance Typical IC50 values associated with its mineralocorticoid receptor binding affinity have been reported in the nanomolar range Based on these pharmacological properties Deoxycorticosterone acetate holds research potential in studies of electrolyte balance adrenal insufficiency modeling and the pathophysiology of hypertension as well as models investigating mineralocorticoid receptor-dependent signaling and renal or cardiovascular physiology
Apexbio Technology LLC Medroxyprogesterone 520-85-4 50mg
Medroxyprogesterone (CAS 520-85-4) is a small-molecule agonist targeting the progesterone receptor It is designed to activate progesterone receptor-mediated intracellular signaling pathways thereby regulating cellular proliferation Medroxyprogesterone exerts its biological activity primarily through agonism of the progesterone receptor modulating pathways such as PI3K/Akt signaling In preclinical mouse models medroxyprogesterone demonstrates inhibitory activity on atherosclerotic lesion formation Based on these pharmacological properties medroxyprogesterone holds research potential in the study of progesterone receptor-mediated biological processes cellular proliferation and vascular pathology
Selleck Chemical LLC Medroxyprogesterone S3635-25mg
Medroxyprogesterone (MP) is a synthetic pregnane steroid and a derivative of progesterone It is a potent progesterone receptor agonist
Medchemexpress LLC Retinol, acetate, 9-cis- | 29584-22-3 | 85.0% | 328.49 | 1 MG
9-cis-Retinol acetate is a retinal derivative developed for research applications. This compound is presented as a solid, typically white to off-white in appearance, with a molecular weight of 328.49. Its purity is 85.0%, making it suitable for various scientific investigations.
- Retinal derivative.
- Intended for research use only.
- Molecular formula C22H32O2.
- Appearance is solid, white to off-white.
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years.
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month.
Apexbio Technology LLC Estradiol Benzoate 50-50-0 10mM (in 1mL DMSO)
Estradiol benzoate (50-50-0) is a small-molecule agonist targeting estrogen receptors exhibiting high binding affinity for estrogen receptor alpha (ER ) It is designed to activate ER thereby modulating estrogen-mediated signaling pathways and hormonal regulation processes Estradiol benzoate exerts its biological activity primarily through ER agonism In in vitro assays involving human murine and chicken ER proteins estradiol benzoate demonstrates agonistic activity with an IC50 value ranging between 22 28 nM Based on these pharmacological properties estradiol benzoate holds research potential in studies of ER-mediated signaling endocrine-related diseases receptor-ligand binding analyses pharmacological screening and investigations of estrogen-dependent physiological and pathological conditions
Medchemexpress LLC Bazedoxifene (acetate)-D | 198481-33-3 | MFCD09260074 | C32H38N2O5 | 100 MG
Bazedoxifene (acetate)-D is a solid compound with a molecular formula of C32H38N2O5 and a molecular weight of 530.65. It is classified as a selective estrogen receptor modulator and a bone density conservation agent. This compound helps to inhibit bone resorption and favor bone mineralization, making it suitable for addressing conditions like osteoporosis and promoting bone fracture healing. It is an FDA-approved, prescription-only drug administered orally.
- Functions as a selective estrogen receptor modulator
- Acts as a bone density conservation agent
- Inhibits bone resorption
- Promotes bone mineralization and regeneration
- Utilized in treating osteoporosis and healing bone fractures
- FDA-approved, available by prescription only
- Administered via oral route
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.88% | C32H38N2O5 | 500 MG
Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM). It has IC50s of 23 nM for ERα and 99 nM for ERβ. This compound is used in the research of osteoporosis. Additionally, Bazedoxifene acetate acts as an inhibitor of IL-6/GP130 protein-protein interactions and is utilized in research for pancreatic cancer.
- Oral, nonsteroidal selective estrogen receptor modulator (SERM)
- Exhibits IC50s of 23 nM for ERα and 99 nM for ERβ
- Used in osteoporosis and pancreatic cancer research
- Inhibits IL-6/GP130 protein-protein interactions and STAT3 phosphorylation
- Induces apoptosis and blocks cell migration in pancreatic cancer cells in vitro
- Inhibits Capan-1 tumor growth in a mouse model in vivo
Medchemexpress LLC Norethisterone enanthate | 3836-23-5 | 99.5% | C27H38O3 | 1 ML
Norethisterone enanthate is a long-acting parenteral progestogen used as an intramuscular contraceptive agent. It is also an orally active click chemistry reagent containing an alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules.
- Long-acting parenteral progestogen
- Functions as an intramuscular contraceptive agent
- Orally active
- Contains an alkyne group for click chemistry applications
- Powder stable at -20°C for 3 years or 4°C for 2 years
- Solution stable at -80°C for 2 years or -20°C for 1 year
- Store stock solutions aliquoted to prevent inactivation from repeated freeze-thaw cycles